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Look younger.
Feel sharper.
Age on your terms.

We read the studies so you don't have to — then tell you what's actually worth your time and money, and what's just marketing.

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New here? These five cut straight through the noise.

Collagen capsules and a serum dropper on linen
Supplements

Does Drinking Your Collagen Actually Do Anything?

Hydrolyzed collagen, “bioactive” peptides, marine collagen — the powder everyone sips. For once, the buzzword has a real stack of human trials behind it.

June 2026 · 7 min read
Older woman in a clinic waiting room after a vaccination, illustrating thymus aging and immune decline
Immune aging

Thymus Regeneration: The Organ That Ages First

It starts shrinking before you can walk. Nine men, one growth-hormone protocol, and the biotech race to regrow the gland that trains your immune system.

8 min read
Woman in her late fifties by a bright window with bare unretouched skin, illustrating skin longevity
Skin

Skin Longevity: What Actually Slows Skin Aging

The industry retired “anti-aging” for “skin longevity”. Only one intervention has ever slowed skin aging in a randomised trial — and it finished in 1996.

8 min read
Dark tar-like shilajit resin in an open glass jar on stone in morning light
Supplements

Shilajit: What the Seven Human Trials Actually Show

TikTok’s favourite resin has a $200m market and exactly seven randomised trials. We read all of them — the testosterone claim rests on one.

8 min read
Grilled chicken breast and lentils beside a glass bottle in morning light, illustrating BCAA supplements and aging
New Research

BCAA Supplements and Aging: What the Valine Study Really Shows

Mice fed less valine lived 23% longer — the males did. What one amino acid says about the tub of powder in your gym bag.

8 min read
Grey-haired man in his fifties running on a misty park path at sunrise, illustrating brain aging after 50
New Research

Brain Aging After 50: The Midlife Immune Cell Swap

Between 50 and 75 the hippocampus loses the immune cells it has had since birth and blood-derived cells move in. A striking 2026 finding — and what it does not prove.

8 min read
Supermarket aisle stacked with plastic-packaged food and bottled water, illustrating everyday exposure behind microplastics and aging
New Research

Microplastics and Aging: What the Evidence Really Shows

Plastic is now measurable in human brains and arteries. The cell data is alarming, the human data is thinner — and the famous “credit card a week” number is wrong.

8 min read
Researcher at a laboratory microscope studying tissue samples, illustrating how cells age at different rates
New Research

Cells Age at Different Rates — and It Breaks the One-Number Age Test

A 2026 Nature Communications study found tissues are a mosaic of fast and slow ageing cells. Every biological age test averages that away.

7 min read
Older woman sitting beside a sunlit window during a summer heatwave, illustrating how heat and aging affect the body
New Research

Heat and Aging: Why Your Body Copes Worse Every Decade

Core temperature climbs 0.08°C per decade in extreme heat — and the slope starts in your twenties. But two 2026 studies found the decline is partly trainable.

8 min read
Open prescription bottle with white tablets spilling onto a laboratory bench, illustrating research into existing drugs that slow aging
New Research

Drugs That Slow Aging — and 23 That May Speed It Up

A June 2026 Nature Aging study ranked 6,442 existing medicines against the biology of aging. The headlines took the wrong half.

8 min read
Plate with a small portion of fish and a large portion of lentils and vegetables, illustrating protein restriction for longevity
New Research

Protein Restriction: Does Eating Less Protein Slow Aging?

A review of 350+ studies published on 31 July 2026 says less protein may slow aging. The age where that advice flips.

8 min read
Woman asleep in blue moonlight illustrating the glymphatic system cleaning the brain during sleep
New Research

Glymphatic System: How Sleep Washes Your Brain Clean

For a decade nobody could prove it in a living person. In January 2026, 39 volunteers finally settled it.

8 min read
Bag of golden blood plasma on an IV stand during therapeutic plasma exchange
New Research

Plasma Exchange and Aging: Can a ‘Blood Swap’ Reverse It?

A 2025 trial found swapping out old plasma rejuvenated 15 aging clocks — while another found the opposite. The honest science.

9 min read
Researcher in a bright laboratory holding a clear cell-culture plate up to the window light during reprogramming research
New Research

Cellular Reprogramming: First Human Trial to Reverse Aging

Scientists just dosed the first person with a therapy designed to make aged cells young again — and it started in the eye. The honest science.

9 min read
Healthy man in his late sixties walking through a park on an autumn morning, illustrating immune system aging
New Research

Immune System Aging: Why Your Defenses Slow Down

Your immune system has an age of its own — the 2026 science on immunosenescence, inflammaging, and what actually slows it.

9 min read
Woman in her sixties strength training to prevent muscle loss with age
New Research

Muscle Loss With Age: Why Structured Exercise Wins

A wave of 2026 research keeps arriving at the same point: staying busy is not the same as training — and grip strength predicts survival.

8 min read
Editorial portrait illustrating glycation and skin aging
New Research

Glycation and Aging: How Sugar Quietly Ages You

The same reaction that browns toast is stiffening your skin and arteries — and scientists just reversed some of it.

9 min read
Macro photograph of a deep blue methylene blue drop falling from a glass pipette into a vial on a lab bench
New Research

Methylene Blue: Does the Viral Brain Tonic Work?

Biohackers dose the 150-year-old blue dye for focus and longevity. The honest human evidence.

8 min read
Scientist’s hands holding a printed DNA methylation data sheet beside sample tubes, epigenetic clock testing
New Research

Epigenetic Clock: The Aging Test That Beat 13 Others

A 2026 study raced 14 aging biomarkers against death. One DNA-based clock won — what it measures, and its limits.

8 min read
Alpha-ketoglutarate capsule and white powder on dark slate
New Research

Alpha-Ketoglutarate: Can AKG Really Reverse Aging?

A new 2026 study links this cheap cell metabolite to a younger biological age. The honest science.

9 min read
BPC-157 peptide vial and syringe on a clinical laboratory surface
Peptides

BPC-157: The Truth About the Viral Healing Peptide

The “Wolverine peptide” is everywhere. What the science actually shows.

8 min read
Creatine monohydrate powder with a scoop and a glass of water
Supplements

Creatine Beyond Muscle: Brain, Cognition and Aging

Famous for muscle — but what does it really do for the aging brain?

10 min read
Amber peptide serum bottle on cream linen
Skincare

Copper Peptides (GHK-Cu): Buzzword With Real Science

What the research actually supports — and where marketing runs ahead.

7 min read
Longevity supplements with berries, lemon and green tea
Supplements

The Longevity Supplements Worth Your Money

Forget the $80 powders. A few cheap, boring basics have the real evidence.

7 min read

Browse by topic

Every guide, organised into three deep-dive hubs.

💊

Longevity Supplements

NAD+, NMN, spermidine, omega-3, peptides, rapamycin — what the human trials actually support, and what's hype.

Explore supplements →
🏃

Longevity Habits

VO₂ max, sleep, protein, sauna and fasting — the free daily basics with the strongest evidence for a longer life.

Explore habits →
💉

GLP-1 & Weight Loss

Ozempic and aging, the muscle trade-off, microdosing and natural alternatives like berberine — the evidence.

Explore GLP-1 →

Free tools

Interactive, science-based calculators — no sign-up, instant results.

Biological Age Calculator

Estimate your biological age from your lifestyle in about 60 seconds.

Try it →

Longevity Score Quiz

Score your daily habits 0–100 and see your top 3 highest-impact gaps.

Try it →

Fitness Age Calculator

Estimate your VO₂ max without a treadmill test — find your fitness age.

Try it →

Protein Calculator

Your daily protein target in grams, from weight, age, activity and goal.

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Sleep Debt Calculator

Work out your weekly sleep debt — and how to pay it back.

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Latest

Fresh research, broken down — every week.

00
Metabolic Health

Retatrutide and Aging: The Strongest Weight-Loss Shot Yet

The next drug in the Ozempic saga hits three hormone systems at once and posts the biggest weight-loss numbers short of surgery — here is what it means for aging.

01
Longevity Science

Immune System Aging: Why Your Defenses Slow Down

A wave of 2026 research says your immune system ages on its own — immunosenescence, inflammaging, and what genuinely slows the drift.

02
Longevity Science

The APOE Gene: Longevity, Alzheimer’s, and Your Aging Brain

One gene, three versions — one turns up in centenarians, one is the top risk gene for Alzheimer’s. New 2026 science on how it protects the aging brain.

03
Brain & Cognition

Methylene Blue: Does the Viral Brain Tonic Work?

The internet’s newest blue “brain tonic” has real mitochondrial science — and a failed Alzheimer’s trial. The honest evidence.

04
Supplements

NMN vs NAD+: What’s the Difference and Which Should You Take?

One is the molecule your cells run on, the other is a building block — and that changes which you should take.

05
Supplements

Spermidine: Benefits, Best Food Sources, and Side Effects

The autophagy-triggering compound in wheat germ and aged cheese — benefits, foods and safety.

06
Supplements

NMN Supplements: Benefits, Side Effects, and How to Choose a Brand

What the trials show, what side effects to expect, and how to spot a product worth the money.

07
New Research

Do Multivitamins Slow Aging? A Big Trial's Honest Answer

A daily multivitamin nudged five biological-age clocks in a 958-person Harvard trial. The effect was real — and smaller than the headlines.

08
Longevity Science

Maximum Human Lifespan: Could We Really Reach 156?

A 2026 model puts the ceiling on human life near 156 years — set by DNA damage in cells that never divide. What that number really means.

09
Longevity Science

Klotho: The Anti-Aging Protein Your Body Already Makes

Mice with extra klotho live longer, and low levels predict earlier death in people. The honest science — and how exercise raises your own.

10
Supplements

Berberine: Nature’s Ozempic or Just Viral Hype?

Social media calls it “nature’s Ozempic.” The real evidence on blood sugar, weight and the viral hype.

11
GLP-1

The Hidden Half of Ozempic Weight Loss: What Happens to Your Muscle

Up to 40% of the weight lost on GLP-1 drugs can be muscle — the tissue that keeps you strong as you age. The science, and how to protect it.

12
Peptides

BPC-157: What the Science Really Says About the Viral Healing Peptide

The “Wolverine peptide” is all over fitness forums and clinics. The honest 2026 evidence — and the human data gap.

13
Longevity

GLP-1 Microdosing: Does a Tiny Ozempic Dose Work?

2026’s buzziest longevity trend is a fraction of a weight-loss shot — taken by people who don’t need to lose weight. The honest science.

14
Longevity

Biological Age Reversal: What the Science Really Shows

Clinics charge six figures to turn back your clock; a viral diet study promises years off in a month. The honest evidence.

15
Longevity

GLP-1 and Aging: Does Ozempic Slow Your Biological Clock?

A 2026 randomized trial found semaglutide slowed a validated aging clock by 9%. The signal — and the catch.

16
Supplements

C15:0: The Dairy Fat Now Called an 'Essential' Nutrient

A saturated fat we were told to avoid is being called the first new essential fatty acid in 90 years.

17
Supplements

Ergothioneine: The 'Longevity Vitamin' From Mushrooms

An obscure mushroom antioxidant falls with age and made mice live longer. The honest science.

18
Supplements

Taurine and Aging: What the Landmark Study Really Found — and What It Didn’t

A top journal called it a driver of aging. The animal data dazzle; the human data are contested.

19
Supplements

Omega-3 and Aging: The Supplement That Actually Slowed a Biological Clock

One of the few supplements to move a validated aging clock in a real randomised trial.

20
Longevity

Rapamycin: The Most Talked-About Longevity Drug, Honestly Assessed

Stunning animal data, real human risks, and what we still don’t know.

21
Fitness

VO₂ Max: The Longevity Metric You’re Probably Ignoring

One fitness number predicts lifespan better than almost any other — and how to raise it.

22
Supplements

NMN and NAD+: What 80 People in a Real Trial Actually Showed

The human data — not the mouse hype — on the supplement everyone’s talking about.

23
Nutrition

Protein After 40: Why Your Needs Go Up Just as Most Eat Less

Your body uses protein less efficiently with age — exactly when most people cut back.

24
Heart Health

Sauna and the Heart: One of Longevity’s Best Bargains

Regular sauna bathing tracks with big drops in heart and all-cause mortality.

25
Sleep

Sleep: The Longevity Intervention You’re Probably Underrating

You can’t biohack your way around bad sleep. The most underrated tool you have.

26
Nutrition

Does Intermittent Fasting Really Beat Just Eating Less?

A Nature Medicine trial put fasting head-to-head with plain calorie cutting.

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